Basic Information
ID: ALA4307471
Type: ADME
Description: Ratio of apparent permeability across apical to basolateral side in presence of P-gp inhibitor elacridar over apical to basolateral side in absence of P-gp inhibitor elacridar in mouse LLC cells transfected with human MDR1 at 5 uM by LC/MS-MS analysis
Organism: Mus musculus
Cell type: Lewis lung carcinoma cell line
Activity Charts
Bioactivity
Activity Types for Assay ALA4307471
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.41 | 2.78 | 2.78 |
| 390.38 | 1.57 | 1.57 |
| 390.38 | 1.57 | 1.57 |
| 391.37 | 0.97 | 0.97 |
| 390.38 | 1.57 | 1.57 |
| 371.40 | 2.04 | 2.04 |
| 389.39 | 2.18 | 2.18 |
| 389.39 | 2.18 | 2.18 |