Basic Information
ID: ALA4307491
Type: Binding
Description: Inhibition of human TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye based FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4307491
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.48 | 3.68 | 3.68 |
| 416.49 | 3.98 | 3.98 |
| 416.48 | 4.50 | 4.50 |
| 404.45 | 4.63 | 4.63 |
| 434.93 | 5.54 | 5.54 |
| 394.52 | 4.73 | 4.73 |
| 446.51 | 4.07 | 4.07 |
| 460.54 | 3.90 | 3.90 |
| 430.51 | 4.89 | 4.89 |
| 408.55 | 5.07 | 5.07 |
| 434.93 | 5.54 | 5.54 |
| 446.51 | 4.07 | 4.07 |
| 404.45 | 4.63 | 4.63 |
| 430.51 | 4.89 | 4.89 |
| 366.47 | 4.09 | 4.09 |
| 444.54 | 5.28 | 5.28 |
| 420.90 | 5.15 | 5.15 |
| 442.52 | 4.55 | 4.55 |
| 414.51 | 5.19 | 5.19 |
| 324.38 | 2.97 | 2.97 |
| 380.49 | 4.34 | 4.34 |
| 386.46 | 4.49 | 4.49 |
| 430.51 | 4.89 | 4.89 |
| 418.47 | 5.02 | 5.02 |
| 400.48 | 4.80 | 4.80 |
| 444.54 | 5.28 | 5.28 |
| 420.90 | 5.15 | 5.15 |
| 445.52 | 4.68 | 4.68 |
| 458.57 | 4.97 | 4.97 |
| 418.47 | 5.02 | 5.02 |