Basic Information
ID: ALA4307530
Type: Functional
Description: Bactericidal activity against serine beta-lactamase producing Mycobacterium tuberculosis H37Rv infected in C57BL/6J mouse BMDM cells assessed as increase in intracellular macrophage killing by measuring inhibition of increase in viable macrophage number at 100 ug/ml preincubated for 6 days post 24 hrs of infection and further incubated in middlebrook 7H11/BSA supplemented with ODAC for 3 weeks by serial dilution based colony counting method
Format: BAO_0000218
Organism: Mycobacterium tuberculosis
Strain: H37Rv
Target: Mycobacterium tuberculosis(ALA360)
Document: ALA4304800
Bactericidal activity against serine beta-lactamase producing Mycobacterium tuberculosis H37Rv infected in C57BL/6J mouse BMDM cells assessed as increase in intracellular macrophage killing by measuring inhibition of increase in viable macrophage number at 100 ug/ml preincubated for 6 days post 24 hrs of infection and further incubated in middlebrook 7H11/BSA supplemented with ODAC for 3 weeks by serial dilution based colony counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4307530
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.34 | 3.94 | 3.94 |
| 416.37 | 4.50 | 4.50 |
| 416.37 | 4.50 | 4.50 |
| 416.37 | 4.50 | 4.50 |