Inhibition of Trypanosoma cruzi cruzain assessed as inhibitor constant using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins f...

Basic Information

ID: ALA4308361

Type: Binding

Description: Inhibition of Trypanosoma cruzi cruzain assessed as inhibitor constant using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition by fluorescence based analysis

Format: BAO_0000357

Organism: Trypanosoma cruzi

Target:  Cruzipain(ALA3563)

Document:  ALA4304821

Inhibition of Trypanosoma cruzi cruzain assessed as inhibitor constant using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition by fluorescence based analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
417.433.673.67
396.804.714.71
353.343.583.58
466.304.434.43
396.804.714.71
417.484.554.55
353.343.583.58
353.393.473.47
483.665.495.49
495.555.005.00
421.854.324.32
421.854.324.32
387.413.663.66
493.576.216.21
429.495.135.13
387.413.663.66
447.485.275.27
417.433.673.67