Basic Information
ID: ALA4308375
Type: Binding
Description: Inhibition of HSP90 at C-terminus in human SKBR3 cells assessed as induction of CDK4 protein degradation at 0.5 to 5 times antiproliferative IC50 incubated for 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Heat shock protein HSP90(ALA2095165)
Document: ALA4304822
Inhibition of HSP90 at C-terminus in human SKBR3 cells assessed as induction of CDK4 protein degradation at 0.5 to 5 times antiproliferative IC50 incubated for 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4308375
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 808.75 | 10.05 | 10.05 |
| 814.71 | 8.80 | 8.80 |
| 814.80 | 9.59 | 9.59 |