Basic Information
ID: ALA4308556
Type: Binding
Description: Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as conversion of arachidonic acid to 5-HPETE at 10 uM using arachidonic acid as substrate in presence of ATP by UV-vis spectrophotometry analysis relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4304831
Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as conversion of arachidonic acid to 5-HPETE at 10 uM using arachidonic acid as substrate in presence of ATP by UV-vis spectrophotometry analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4308556
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 396.44 | 4.75 | 4.75 |
| 356.38 | 4.33 | 4.33 |
| 380.44 | 5.05 | 5.05 |
| 393.42 | 4.51 | 4.51 |
| 338.39 | 4.19 | 4.19 |
| 348.43 | 4.60 | 4.60 |
| 438.51 | 4.63 | 4.63 |
| 354.46 | 4.66 | 4.66 |
| 408.48 | 4.62 | 4.62 |
| 372.45 | 4.80 | 4.80 |
| 366.42 | 4.74 | 4.74 |
| 409.49 | 4.81 | 4.81 |
| 489.32 | 5.23 | 5.23 |
| 427.32 | 5.36 | 5.36 |
| 382.87 | 5.25 | 5.25 |
| 378.45 | 4.61 | 4.61 |
| 427.32 | 5.36 | 5.36 |
| 427.87 | 5.16 | 5.16 |
| 391.50 | 4.67 | 4.67 |
| 392.48 | 4.92 | 4.92 |
| 471.33 | 5.09 | 5.09 |
| 362.45 | 4.91 | 4.91 |