Basic Information
ID: ALA4308557
Type: Binding
Description: Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as conversion of arachidonic acid to 5-HPETE using arachidonic acid as substrate in presence of ATP by UV-vis spectrophotometry analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4304831
Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as conversion of arachidonic acid to 5-HPETE using arachidonic acid as substrate in presence of ATP by UV-vis spectrophotometry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4308557
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 396.44 | 4.75 | 4.75 |
| 380.44 | 5.05 | 5.05 |
| 393.42 | 4.51 | 4.51 |
| 438.51 | 4.63 | 4.63 |
| 366.42 | 4.74 | 4.74 |
| 391.50 | 4.67 | 4.67 |
| 392.48 | 4.92 | 4.92 |
| 471.33 | 5.09 | 5.09 |