Basic Information
ID: ALA4308998
Type: Binding
Description: Negative allosteric modulation of human GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel current at -40 mV holding potential by two electrode voltage clamp method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4308998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.45 | 3.77 | 3.77 |
| 461.90 | 3.03 | 3.03 |
| 470.94 | 1.95 | 1.95 |
| 468.51 | 1.74 | 1.74 |