Basic Information
ID: ALA4309192
Type: ADME
Description: Antagonist activity at prolink-tagged TrkB (unknown origin) expressed in cells assessed as inhibition of BDNF-induced receptor phosphorylation by measuring reduction in EA-tagged SH2 protein recruitment preincubated for 30 mins followed by BDNF addition measured after 2 hrs by PathHunter enzyme complementation assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4309192
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.22 | 4.74 | 4.74 |
| 432.87 | 3.52 | 3.52 |