Basic Information
ID: ALA4309257
Type: Binding
Description: Activation of recombinant His-tagged human cytosolic GPX4 U46C mutant expressed in Escherichia coli M15 assessed as increase in oxidized glutathione-mediated oxidation of NADPH to NADP+ using tert-butyl hydroperoxide as substrate preincubated for 5 mins followed by substrate addition measured for 6 mins by glutathione reductase enzyme coupled fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4309257
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 355.87 | 2.89 | 2.89 |
| 321.43 | 2.23 | 2.23 |
| 314.44 | 0.50 | 0.50 |
| 392.98 | 1.41 | 1.41 |
| 392.98 | 1.54 | 1.54 |
| 378.95 | 1.15 | 1.15 |
| 366.94 | 1.01 | 1.01 |
| 275.36 | -0.39 | -0.39 |