Basic Information
ID: ALA4309274
Type: Binding
Description: Activation of recombinant human GPX4 D21A/U46C double mutant expressed in Escherichia coli M15 assessed as increase in oxidized glutathione-mediated oxidation of NADPH to NADP+ using tert-butyl hydroperoxide as substrate preincubated for 5 mins followed by substrate addition measured for 6 mins by glutathione reductase enzyme coupled fluorescence assay relative to GPX4 U46C mutant control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4309274
EC150
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 355.87 | 2.89 | 2.89 |
| 378.95 | 1.15 | 1.15 |