Basic Information
ID: ALA4309295
Type: Binding
Description: Inhibition of human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as reduction in [3H]MTX uptake at pH 5.5 at 1 uM measured over 2 mins relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4309295
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.47 | 1.45 | 1.45 |
| 441.44 | 1.06 | 1.06 |
| 427.42 | 0.67 | 0.67 |
| 573.57 | 1.29 | 1.29 |
| 447.47 | 1.12 | 1.12 |
| 461.50 | 1.51 | 1.51 |
| 447.47 | 1.12 | 1.12 |
| 456.46 | 0.84 | 0.84 |
| 465.46 | 1.26 | 1.26 |
| 479.49 | 1.65 | 1.65 |
| 459.43 | 1.20 | 1.20 |
| 473.46 | 1.59 | 1.59 |
| 474.45 | 0.98 | 0.98 |