Basic Information
ID: ALA4309300
Type: Binding
Description: Inhibition of GARFTase in human IGROV1 cells assessed as decrease in incorporation of [14C(U)glycine into [14C]formyl GAR formation after 24 hrs
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4309300
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.47 | 1.45 | 1.45 |
| 441.44 | 1.06 | 1.06 |
| 427.42 | 0.67 | 0.67 |
| 447.47 | 1.12 | 1.12 |
| 461.50 | 1.51 | 1.51 |
| 447.47 | 1.12 | 1.12 |
| 456.46 | 0.84 | 0.84 |
| 465.46 | 1.26 | 1.26 |
| 479.49 | 1.65 | 1.65 |
| 459.43 | 1.20 | 1.20 |
| 473.46 | 1.59 | 1.59 |
| 474.45 | 0.98 | 0.98 |