Toxicity in NCR SCID mouse xenografted with human IGROV1 cells assessed as weight loss median nadir at 95 mg/kg, iv treated once daily for 4 days per ...

Basic Information

ID: ALA4309322

Type: Toxicity

Description: Toxicity in NCR SCID mouse xenografted with human IGROV1 cells assessed as weight loss median nadir at 95 mg/kg, iv treated once daily for 4 days per week for 4 weeks starting from 3 days post implantation and measured at day 18 post last dose relative to control

Format: BAO_0000218

Organism: Mus musculus

Strain: NCR

Target:  ADMET(ALA612558)

Document:  ALA4308835

Toxicity in NCR SCID mouse xenografted with human IGROV1 cells assessed as weight loss median nadir at 95 mg/kg, iv treated once daily for 4 days per week for 4 weeks starting from 3 days post implantation and measured at day 18 post last dose relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
479.491.651.65