Basic Information
ID: ALA4309373
Type: Binding
Description: Inhibition of IDH2 R140Q mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 60 mins by by diaphorase and resazurin dye based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4309373
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.38 | 4.29 | 4.29 |
| 493.43 | 5.33 | 5.33 |
| 442.36 | 4.43 | 4.43 |
| 460.43 | 5.24 | 5.24 |
| 381.41 | 3.50 | 3.50 |