Basic Information
ID: ALA4310046
Type: Binding
Description: Positive allosteric modulation of rat mGlu4 receptor expressed in HEK cells co-expressing GIRK1/2 assessed as increase in glutamate-induced thallium flux preincubated for 140 secs followed by glutamate addition and measured after 2.5 mins by FluoZin-2-AM dye based fluorescence assay relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Metabotropic glutamate receptor 4(ALA2787)
Document: ALA4308847
Positive allosteric modulation of rat mGlu4 receptor expressed in HEK cells co-expressing GIRK1/2 assessed as increase in glutamate-induced thallium flux preincubated for 140 secs followed by glutamate addition and measured after 2.5 mins by FluoZin-2-AM dye based fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4310046
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.37 | 3.83 | 3.83 |
| 319.37 | 4.50 | 4.50 |
| 305.34 | 4.11 | 4.11 |
| 380.43 | 2.78 | 2.78 |
| 266.26 | 2.55 | 2.55 |
| 320.36 | 3.90 | 3.90 |
| 283.27 | 3.29 | 3.29 |
| 308.37 | 3.58 | 3.58 |
| 315.28 | 3.95 | 3.95 |
| 265.28 | 3.15 | 3.15 |
| 283.27 | 3.29 | 3.29 |
| 283.27 | 3.29 | 3.29 |
| 401.45 | 3.94 | 3.94 |
| 307.38 | 4.19 | 4.19 |
| 401.40 | 3.23 | 3.23 |
| 408.49 | 3.56 | 3.56 |
| 414.44 | 4.18 | 4.18 |
| 265.28 | 3.15 | 3.15 |
| 414.44 | 4.18 | 4.18 |
| 321.38 | 4.43 | 4.43 |
| 295.37 | 3.87 | 3.87 |
| 321.38 | 4.75 | 4.75 |
| 338.44 | 4.29 | 4.29 |
| 339.43 | 3.69 | 3.69 |
| 283.27 | 3.29 | 3.29 |
| 279.30 | 3.41 | 3.41 |
| 400.41 | 3.84 | 3.84 |
| 392.49 | 4.04 | 4.04 |