Basic Information
ID: ALA4310116
Type: Binding
Description: Inhibition of BRD4 bromodomain 1 in human A549 cells assessed as reduction in TNFalpha-induced NFkappaB transcription at 10 uM after 8 hrs by bright-glo luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Bromodomain-containing protein 4(ALA1163125)
Document: ALA4308848
Inhibition of BRD4 bromodomain 1 in human A549 cells assessed as reduction in TNFalpha-induced NFkappaB transcription at 10 uM after 8 hrs by bright-glo luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4310116
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.54 | 5.43 | 5.43 |