Basic Information
ID: ALA4310246
Type: Binding
Description: Positive allosteric modulation of GABA-A alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 30 uM after 5 mins at -70 mV holding potential by two-microelectrode voltage clamp method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4310246
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 235.07 | 2.85 | 2.85 |
| 274.54 | 3.78 | 3.78 |
| 234.34 | 3.79 | 3.79 |
| 216.07 | 3.28 | 3.28 |
| 216.07 | 3.28 | 3.28 |
| 207.28 | 4.08 | 4.08 |
| 191.66 | 3.58 | 3.58 |
| 231.26 | 1.00 | 1.00 |
| 171.24 | 3.23 | 3.23 |
| 238.68 | 2.30 | 2.30 |
| 218.26 | 1.96 | 1.96 |
| 214.09 | 4.01 | 4.01 |
| 212.08 | 3.92 | 3.92 |
| 214.09 | 3.70 | 3.70 |
| 238.68 | 2.30 | 2.30 |
| 193.68 | 3.67 | 3.67 |
| 188.23 | 1.85 | 1.85 |
| 195.65 | 2.94 | 2.94 |
| 212.08 | 3.92 | 3.92 |
| 255.10 | 2.78 | 2.78 |
| 230.09 | 2.88 | 2.88 |
| 193.68 | 3.35 | 3.35 |
| 259.10 | 2.65 | 2.65 |
| 191.66 | 3.58 | 3.58 |
| 212.08 | 3.92 | 3.92 |
| 255.10 | 2.78 | 2.78 |
| 255.10 | 2.78 | 2.78 |
| 195.65 | 2.94 | 2.94 |
| 195.65 | 2.94 | 2.94 |
| 214.27 | 2.38 | 2.38 |
| 237.09 | 3.81 | 3.81 |
| 214.65 | 2.50 | 2.50 |
| 179.17 | 2.89 | 2.89 |
| 207.28 | 4.08 | 4.08 |
| 296.13 | 1.45 | 1.45 |
| 175.23 | 2.59 | 2.59 |
| 212.08 | 3.92 | 3.92 |
| 191.66 | 3.58 | 3.58 |
| 191.66 | 3.58 | 3.58 |
| 230.09 | 2.88 | 2.88 |
| 179.17 | 2.89 | 2.89 |