Assay Report Card

Basic Information

ID: ALA4310261

Type: Binding

Description: Positive allosteric modulation of GABA-A alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GABA-induced chloride current at 10 to 100 uM co-treated with GABA for 20 secs followed by compound washout and measured after 5 mins at -70 mV holding potential by two-microelectrode voltage clamp method

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
237.093.813.81
212.083.923.92