Basic Information
ID: ALA4310268
Type: Binding
Description: Positive allosteric modulation of GABA-A receptor in Sprague-Dawley rat primary hippocampal neurons assessed as channel-mediated tonic current at 10 uM pretreated for 300 secs followed by BMI addition for 10 secs at -70 mV holding potential by patch-clamp method (Rvb = -37 to -22 pA)
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4310268
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 237.09 | 3.81 | 3.81 |
| 212.08 | 3.92 | 3.92 |