Assay Report Card

Basic Information

ID: ALA4310269

Type: Binding

Description: Positive allosteric modulation of GABA-A receptor in Sprague-Dawley rat primary hippocampal neurons assessed as channel-mediated tonic current at 30 uM pretreated for 300 secs followed by BMI addition for 10 secs at -70 mV holding potential by patch-clamp method (Rvb = -63 pA)

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
234.343.793.79