Basic Information
ID: ALA4310375
Type: Binding
Description: Ratio of partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in peak current amplitude relative to ACh to partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in net charge relative to ACh
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA4308856
Ratio of partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in peak current amplitude relative to ACh to partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in net charge relative to ACh: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4310375
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.45 | 2.63 | 2.63 |
| 399.45 | 2.93 | 2.93 |
| 385.42 | 2.62 | 2.62 |
| 464.32 | 3.38 | 3.38 |
| 441.31 | 2.77 | 2.77 |
| 375.38 | 2.21 | 2.21 |
| 537.18 | 3.37 | 3.37 |
| 386.41 | 2.02 | 2.02 |
| 403.41 | 2.76 | 2.76 |
| 415.45 | 2.63 | 2.63 |
| 412.28 | 2.16 | 2.16 |
| 429.28 | 2.90 | 2.90 |
| 490.18 | 3.53 | 3.53 |
| 453.42 | 3.64 | 3.64 |
| 386.41 | 2.02 | 2.02 |
| 417.32 | 2.83 | 2.83 |
| 441.31 | 2.77 | 2.77 |
| 419.87 | 3.27 | 3.27 |
| 349.22 | 1.41 | 1.41 |
| 479.28 | 3.78 | 3.78 |
| 511.32 | 3.23 | 3.23 |
| 401.25 | 2.36 | 2.36 |
| 323.35 | 1.26 | 1.26 |
| 445.73 | 3.42 | 3.42 |
| 425.31 | 3.07 | 3.07 |
| 411.29 | 2.77 | 2.77 |
| 391.45 | 2.68 | 2.68 |
| 412.28 | 2.16 | 2.16 |