Basic Information
ID: ALA4310471
Type: Binding
Description: Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux preincubated for 2.3 mins followed by glutamate addition measured after 2.6 mins by BTC-AM-dye based fluorescence assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4310471
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.35 | 3.63 | 3.63 |
| 399.49 | 3.81 | 3.81 |