Assay Report Card

Basic Information

ID: ALA4310883

Type: Functional

Description: Antialzheimer activity in Caenorhabditis elegans CL4176 harboring temperature-inducible human amyloid beta transgene assessed as reduction in amyloid beta aggregation at 1 mM pretreated for 48 hrs at 15 degC followed by heat stress stimulation to 25 degC for 35 hrs by thioflavin-s staining based microscopic analysis

Organism: Caenorhabditis elegans

Strain: CL4176

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
507.576.376.37
552.087.507.50
521.606.686.68
533.646.556.55
521.606.686.68
636.488.018.01