Basic Information
ID: ALA4311241
Type: Binding
Description: Inhibition of PDK in human NCI-H1975 cells assessed as switch of pyruvate metabolism from lactate production to oxidative phosphorylation by measuring increase in ROS production at 1 to 10 uM measured after 4 hrs by DCFH-DA dye based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: Pyruvate dehydrogenase kinase(ALA2096665)
Document: ALA4308888
Inhibition of PDK in human NCI-H1975 cells assessed as switch of pyruvate metabolism from lactate production to oxidative phosphorylation by measuring increase in ROS production at 1 to 10 uM measured after 4 hrs by DCFH-DA dye based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4311241
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.50 | 2.89 | 2.89 |