Basic Information
ID: ALA4311584
Type: ADME
Description: Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate assessed as percent enzyme activity at 1 uM after 30 mins in presence of NADPH by EROD assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4311584
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.30 | 4.61 | 4.61 |
| 287.32 | 4.20 | 4.20 |
| 287.32 | 4.20 | 4.20 |
| 264.32 | 4.60 | 4.60 |
| 278.35 | 4.99 | 4.99 |
| 288.30 | 4.32 | 4.32 |
| 288.30 | 4.32 | 4.32 |
| 302.33 | 4.62 | 4.62 |
| 302.33 | 4.62 | 4.62 |
| 294.35 | 3.96 | 3.96 |
| 319.36 | 5.28 | 5.28 |
| 293.37 | 3.93 | 3.93 |
| 352.46 | 5.25 | 5.25 |
| 330.43 | 5.41 | 5.41 |
| 276.34 | 4.77 | 4.77 |
| 310.42 | 4.90 | 4.90 |
| 319.36 | 5.28 | 5.28 |
| 304.37 | 4.90 | 4.90 |
| 375.45 | 5.39 | 5.39 |
| 308.38 | 4.21 | 4.21 |
| 288.35 | 4.63 | 4.63 |
| 375.45 | 5.39 | 5.39 |
| 276.33 | 4.90 | 4.90 |
| 372.44 | 3.95 | 3.95 |
| 294.35 | 3.96 | 3.96 |
| 372.44 | 3.95 | 3.95 |
| 304.37 | 4.90 | 4.90 |
| 319.36 | 5.28 | 5.28 |
| 293.37 | 3.93 | 3.93 |
| 294.35 | 3.96 | 3.96 |
| 352.46 | 5.25 | 5.25 |
| 320.43 | 5.88 | 5.88 |
| 375.45 | 4.84 | 4.84 |
| 313.32 | 5.56 | 5.56 |
| 310.42 | 4.90 | 4.90 |
| 313.32 | 5.56 | 5.56 |
| 293.37 | 3.93 | 3.93 |
| 302.37 | 4.85 | 4.85 |
| 316.40 | 5.56 | 5.56 |
| 294.35 | 3.96 | 3.96 |
| 372.44 | 3.95 | 3.95 |
| 352.46 | 5.25 | 5.25 |
| 372.44 | 3.95 | 3.95 |
| 292.38 | 5.24 | 5.24 |
| 386.47 | 4.20 | 4.20 |
| 302.37 | 4.85 | 4.85 |
| 288.35 | 4.63 | 4.63 |
| 333.39 | 5.53 | 5.53 |
| 310.42 | 4.90 | 4.90 |
| 375.45 | 4.84 | 4.84 |
| 316.40 | 5.56 | 5.56 |