Assay Report Card

Basic Information

ID: ALA4311619

Type: Binding

Description: Inhibition of calf thymus DNA topoisomerase 1 assessed as reduction in enzyme-mediated relaxation of supercoiled pBR322 plasmid DNA at 10 uM after 30 mins by ethidium bromide staining-based agarose gel electrophoresis

Organism: Bos taurus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
348.362.082.08
499.485.165.16
817.694.394.39
377.354.014.01
391.384.024.02
562.504.044.04