Basic Information
ID: ALA4311709
Type: Binding
Description: Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl-alpha -D-glucopyranoside by microbeta counting method
Format: BAO_0000219
Organism: Homo sapiens
Target: Sodium/glucose cotransporter 1(ALA4979)
Document: ALA4308914
Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl-alpha -D-glucopyranoside by microbeta counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4311709
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 738.97 | 2.53 | 2.53 |
| 585.74 | 2.86 | 2.86 |
| 559.68 | 2.47 | 2.47 |
| 683.89 | 3.02 | 3.02 |
| 571.71 | 2.34 | 2.34 |
| 541.69 | 2.34 | 2.34 |
| 667.84 | 2.30 | 2.30 |
| 681.87 | 2.64 | 2.64 |
| 583.77 | 3.46 | 3.46 |
| 571.71 | 2.55 | 2.55 |
| 576.13 | 2.99 | 2.99 |
| 683.89 | 2.84 | 2.84 |
| 555.71 | 2.64 | 2.64 |
| 669.86 | 2.54 | 2.54 |
| 681.87 | 2.63 | 2.63 |
| 669.86 | 2.72 | 2.72 |
| 543.66 | 1.73 | 1.73 |
| 585.74 | 2.85 | 2.85 |
| 669.86 | 2.54 | 2.54 |
| 724.94 | 2.19 | 2.19 |
| 667.84 | 2.29 | 2.29 |
| 599.77 | 3.16 | 3.16 |