ID: ALA4311836
Type: Binding
Description: Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by chemifluorescence assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4311836
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
161.20 | 1.28 | 1.28 |
256.26 | 1.68 | 1.68 |
147.18 | 0.97 | 0.97 |
306.29 | 3.36 | 3.36 |
257.72 | 3.29 | 3.29 |
291.27 | 3.66 | 3.66 |
276.34 | 3.43 | 3.43 |
277.33 | 2.82 | 2.82 |
226.07 | 1.74 | 1.74 |
161.20 | 1.28 | 1.28 |
256.28 | 2.48 | 2.48 |
238.29 | 2.34 | 2.34 |
237.30 | 2.56 | 2.56 |
272.74 | 3.00 | 3.00 |
237.30 | 2.95 | 2.95 |
306.29 | 3.36 | 3.36 |
238.29 | 2.34 | 2.34 |
226.07 | 1.74 | 1.74 |
223.28 | 2.64 | 2.64 |
241.26 | 2.78 | 2.78 |
237.30 | 2.95 | 2.95 |
265.31 | 2.84 | 2.84 |
223.28 | 2.64 | 2.64 |
288.35 | 3.50 | 3.50 |
256.28 | 2.48 | 2.48 |