Basic Information
ID: ALA4311837
Type: Binding
Description: Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by chemifluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4311837
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 161.20 | 1.28 | 1.28 |
| 256.26 | 1.68 | 1.68 |
| 147.18 | 0.97 | 0.97 |
| 306.29 | 3.36 | 3.36 |
| 257.72 | 3.29 | 3.29 |
| 291.27 | 3.66 | 3.66 |
| 276.34 | 3.43 | 3.43 |
| 277.33 | 2.82 | 2.82 |
| 226.07 | 1.74 | 1.74 |
| 161.20 | 1.28 | 1.28 |
| 256.28 | 2.48 | 2.48 |
| 238.29 | 2.34 | 2.34 |
| 237.30 | 2.56 | 2.56 |
| 272.74 | 3.00 | 3.00 |
| 237.30 | 2.95 | 2.95 |
| 306.29 | 3.36 | 3.36 |
| 238.29 | 2.34 | 2.34 |
| 226.07 | 1.74 | 1.74 |
| 223.28 | 2.64 | 2.64 |
| 241.26 | 2.78 | 2.78 |
| 237.30 | 2.95 | 2.95 |
| 265.31 | 2.84 | 2.84 |
| 223.28 | 2.64 | 2.64 |
| 288.35 | 3.50 | 3.50 |
| 256.28 | 2.48 | 2.48 |