Basic Information
ID: ALA4311872
Type: Binding
Description: Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4311872
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 253.32 | 0.98 | 0.98 |
| 408.55 | 1.94 | 1.94 |
| 422.92 | 4.27 | 4.27 |
| 527.66 | 5.36 | 5.36 |
| 563.81 | 7.05 | 7.05 |
| 590.19 | 7.26 | 7.26 |
| 537.73 | 5.86 | 5.86 |
| 657.24 | 5.30 | 5.30 |
| 507.70 | 5.91 | 5.91 |
| 541.69 | 5.61 | 5.61 |
| 521.73 | 6.16 | 6.16 |
| 528.12 | 6.25 | 6.25 |
| 652.26 | 8.36 | 8.36 |
| 528.12 | 6.11 | 6.11 |
| 535.75 | 6.41 | 6.41 |
| 523.70 | 5.61 | 5.61 |
| 547.77 | 6.72 | 6.72 |
| 549.78 | 6.80 | 6.80 |
| 542.15 | 6.50 | 6.50 |
| 540.13 | 6.25 | 6.25 |
| 542.15 | 6.50 | 6.50 |
| 570.20 | 7.28 | 7.28 |
| 542.15 | 6.50 | 6.50 |
| 509.67 | 5.22 | 5.22 |
| 528.12 | 6.25 | 6.25 |
| 566.18 | 5.98 | 5.98 |
| 626.22 | 7.85 | 7.85 |
| 582.21 | 7.43 | 7.43 |
| 527.66 | 5.36 | 5.36 |
| 542.15 | 6.65 | 6.65 |
| 626.22 | 7.85 | 7.85 |
| 521.73 | 6.16 | 6.16 |
| 542.15 | 6.50 | 6.50 |
| 545.65 | 5.50 | 5.50 |
| 533.74 | 6.48 | 6.48 |
| 568.18 | 7.04 | 7.04 |
| 600.19 | 6.18 | 6.18 |
| 556.17 | 6.89 | 6.89 |
| 576.16 | 6.70 | 6.70 |
| 541.69 | 5.61 | 5.61 |
| 523.70 | 5.47 | 5.47 |