Basic Information
ID: ALA4311887
Type: Binding
Description: Inhibition of SQS in rat liver microsomes assessed as reduction in [3H]FPP conversion to squalene preincubated for 10 mins followed by [3H]FPP addition and measured after 10 mins by scintillation counting method
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4311887
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.86 | 9.91 | 9.91 |
| 250.29 | 2.49 | 2.49 |
| 374.32 | 4.28 | 4.28 |
| 350.26 | 2.46 | 2.46 |
| 386.33 | 4.93 | 4.93 |
| 408.34 | 2.87 | 2.87 |
| 504.49 | 4.97 | 4.97 |
| 488.42 | 4.03 | 4.03 |
| 503.39 | 4.24 | 4.24 |
| 388.35 | 4.67 | 4.67 |
| 533.42 | 4.25 | 4.25 |
| 390.32 | 3.38 | 3.38 |
| 424.40 | 3.80 | 3.80 |
| 404.35 | 3.77 | 3.77 |
| 334.26 | 3.36 | 3.36 |
| 458.40 | 4.02 | 4.02 |
| 350.33 | 4.07 | 4.07 |
| 474.46 | 4.96 | 4.96 |
| 243.38 | 3.56 | 3.56 |