Potency index, ratio of 2-(biphenyl-4-yl)-4-methylmorpholin-2-ol hydrobromide IC50 to compound IC50 for inhibition of SQS in rat liver microsomes

Basic Information

ID: ALA4311889

Type: Binding

Description: Potency index, ratio of 2-(biphenyl-4-yl)-4-methylmorpholin-2-ol hydrobromide IC50 to compound IC50 for inhibition of SQS in rat liver microsomes

Format: BAO_0000251

Organism: Rattus norvegicus

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Squalene synthetase(ALA3815)

Document:  ALA4308920

Potency index, ratio of 2-(biphenyl-4-yl)-4-methylmorpholin-2-ol hydrobromide IC50 to compound IC50 for inhibition of SQS in rat liver microsomes: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
504.494.974.97
424.403.803.80
474.464.964.96