Potency index, ratio of 4-methyl-2-(4-(naphthalen-2-yl)phenyl)morpholin-2-ol hydrobromide IC50 to compound IC50 for inhibition of SQS in rat liver mic...

Basic Information

ID: ALA4311890

Type: Binding

Description: Potency index, ratio of 4-methyl-2-(4-(naphthalen-2-yl)phenyl)morpholin-2-ol hydrobromide IC50 to compound IC50 for inhibition of SQS in rat liver microsomes

Format: BAO_0000251

Organism: Rattus norvegicus

Tissue: Liver

Subcellular Fraction: Microsomes

Target: Squalene synthetase(ALA3815)

Document: ALA4308920

Potency index, ratio of 4-methyl-2-(4-(naphthalen-2-yl)phenyl)morpholin-2-ol hydrobromide IC50 to compound IC50 for inhibition of SQS in rat liver microsomes: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4311890

Ratio IC50

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
504.49	4.97	4.97
424.40	3.80	3.80
474.46	4.96	4.96

Parent Molecular Weight

ALogP

Polar Surface Area

504.49

4.97

424.40

3.80

474.46

4.96

Potency index, ratio of 4-methyl-2-(4-(naphthalen-2-yl)phenyl)morpholin-2-ol hydrobromide IC50 to compound IC50 for inhibition of SQS in rat liver mic...

Basic Information

Activity Charts

Compound Summary