Basic Information
ID: ALA4312127
Type: Binding
Description: Inhibition of N-terminal GST-tagged recombinant human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as reduction in NADPH production using S-tetralol as substrate in presence of NADP+ by fluorimetry assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Aldo-keto-reductase family 1 member C3(ALA4681)
Document: ALA4311934
Inhibition of N-terminal GST-tagged recombinant human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as reduction in NADPH production using S-tetralol as substrate in presence of NADP+ by fluorimetry assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4312127
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.37 | 3.10 | 3.10 |
| 275.26 | 1.13 | 1.13 |
| 331.37 | 2.09 | 2.09 |
| 247.29 | 0.72 | 0.72 |