Basic Information
ID: ALA4312178
Type: Binding
Description: Inhibition of human recombinant SIRT1 using p53 (379 to 382 residues) conjugated to AMC as substrate incubated for 45 mins in presence of NAD+ by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 1(ALA4506)
Document: ALA4311938
Inhibition of human recombinant SIRT1 using p53 (379 to 382 residues) conjugated to AMC as substrate incubated for 45 mins in presence of NAD+ by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4312178
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.71 | 2.73 | 2.73 |
| 434.28 | 6.35 | 6.35 |
| 454.64 | 4.78 | 4.78 |
| 310.31 | 3.14 | 3.14 |
| 334.30 | 4.43 | 4.43 |
| 350.30 | 4.31 | 4.31 |
| 345.20 | 4.17 | 4.17 |
| 300.75 | 4.06 | 4.06 |