Basic Information
ID: ALA4312246
Type: Binding
Description: Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo assay
Format: BAO_0000357
Organism: Homo sapiens
Target: PI3-kinase p110-alpha subunit(ALA4005)
Document: ALA4311940
Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4312246
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.40 | 1.81 | 1.81 |
| 508.56 | 2.14 | 2.14 |
| 489.55 | 2.82 | 2.82 |
| 601.63 | 4.92 | 4.92 |
| 442.49 | 4.37 | 4.37 |
| 456.52 | 4.76 | 4.76 |
| 424.50 | 4.23 | 4.23 |
| 652.64 | 3.51 | 3.51 |
| 573.58 | 4.14 | 4.14 |
| 438.53 | 4.62 | 4.62 |
| 479.47 | 2.94 | 2.94 |
| 503.58 | 3.22 | 3.22 |
| 493.50 | 2.96 | 2.96 |
| 531.64 | 4.00 | 4.00 |
| 465.45 | 2.55 | 2.55 |
| 461.48 | 2.43 | 2.43 |
| 493.50 | 2.96 | 2.96 |
| 507.53 | 3.35 | 3.35 |
| 629.69 | 5.70 | 5.70 |
| 414.44 | 3.59 | 3.59 |
| 340.34 | 1.89 | 1.89 |
| 666.67 | 3.90 | 3.90 |
| 493.50 | 3.33 | 3.33 |
| 479.47 | 2.57 | 2.57 |
| 489.54 | 3.21 | 3.21 |
| 475.51 | 2.82 | 2.82 |
| 587.61 | 4.53 | 4.53 |
| 517.61 | 3.61 | 3.61 |
| 428.46 | 3.98 | 3.98 |
| 410.47 | 3.84 | 3.84 |
| 507.53 | 3.35 | 3.35 |
| 382.42 | 3.06 | 3.06 |
| 368.39 | 2.67 | 2.67 |
| 615.66 | 5.31 | 5.31 |
| 475.51 | 2.82 | 2.82 |
| 559.55 | 3.75 | 3.75 |
| 396.45 | 3.45 | 3.45 |