Basic Information
ID: ALA4312545
Type: ADME
Description: Substrate activity at recombinant human UGT1A4 expressed in baculovirus infected insect cell membranes assessed as enzyme-mediated glucuronidation by measuring PT2639 formation at 50 uM preincubated for 5 mins followed by UDPGA addition and measured after 60 mins by LC-MS/MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: UDP-glucuronosyltransferase 1A4(ALA3619)
Document: ALA4311943
Substrate activity at recombinant human UGT1A4 expressed in baculovirus infected insect cell membranes assessed as enzyme-mediated glucuronidation by measuring PT2639 formation at 50 uM preincubated for 5 mins followed by UDPGA addition and measured after 60 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4312545
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.35 | 3.12 | 3.12 |