Basic Information
ID: ALA4312568
Type: ADME
Description: Substrate activity at UGT2B17 in human intestinal microsomes assessed as enzyme-mediated glucuronidation by measuring Km at 2 to 1000 uM preincubated for 5 mins followed by UDPGA addition and measured after 60 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Intestine
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4312568
Km
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.36 | 2.82 | 2.82 |
| 365.36 | 2.82 | 2.82 |
| 383.35 | 3.12 | 3.12 |
| 347.37 | 2.87 | 2.87 |
| 401.34 | 3.59 | 3.59 |
| 365.36 | 3.34 | 3.34 |
| 383.35 | 3.29 | 3.29 |