Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HT...

Basic Information

ID: ALA4312768

Type: Binding

Description: Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay

Format: BAO_0000357

Organism: Homo sapiens

Target: PI3-kinase p110-alpha subunit(ALA4005)

Document: ALA4311944

Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4312768

IC50

Total(36)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
433.53	2.05	2.05
493.66	1.93	1.93
419.51	1.67	1.67
461.59	1.81	1.81
363.44	1.62	1.62
490.65	2.38	2.38
458.58	2.26	2.26
433.53	1.07	1.07
271.32	2.07	2.07
338.41	2.96	2.96
360.44	2.07	2.07
256.30	2.74	2.74
388.49	2.81	2.81
341.42	2.51	2.51
430.53	2.51	2.51
338.41	2.96	2.96
388.49	2.81	2.81
458.58	3.24	3.24
327.39	2.12	2.12
430.53	2.51	2.51
391.49	2.35	2.35
338.41	2.96	2.96
268.32	2.53	2.53
257.29	1.69	1.69
458.58	3.24	3.24
324.38	3.09	3.09
254.29	2.65	2.65
268.32	2.53	2.53
268.32	2.53	2.53
490.65	2.38	2.38
430.53	1.52	1.52
430.53	1.52	1.52
461.59	2.79	2.79
360.44	2.07	2.07
346.41	2.20	2.20
458.58	2.26	2.26