Basic Information
ID: ALA4312827
Type: Binding
Description: Inhibition of full-length C-terminal his-tagged human acidic mammalian chitinase expressed in CHOK1 cells assessed as reduction in chitinolytic activity using 4-methylumbelliferyl-beta-D-N,N-diacetylchitobioside hydrate as substrate after 60 mins by fluorometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4312827
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.89 | 1.95 | 1.95 |
| 360.89 | 2.89 | 2.89 |
| 392.94 | 2.59 | 2.59 |
| 376.89 | 1.69 | 1.69 |
| 392.94 | 2.32 | 2.32 |
| 441.99 | 1.10 | 1.10 |
| 441.99 | 1.10 | 1.10 |
| 378.91 | 1.93 | 1.93 |
| 376.89 | 1.95 | 1.95 |
| 418.97 | 3.12 | 3.12 |
| 378.91 | 1.93 | 1.93 |
| 376.89 | 1.95 | 1.95 |
| 390.92 | 2.34 | 2.34 |
| 405.93 | 1.69 | 1.69 |
| 392.94 | 2.59 | 2.59 |
| 378.91 | 2.20 | 2.20 |
| 391.91 | 1.30 | 1.30 |
| 390.92 | 2.34 | 2.34 |
| 404.95 | 2.73 | 2.73 |
| 378.86 | 1.64 | 1.64 |
| 406.96 | 2.98 | 2.98 |
| 376.89 | 1.69 | 1.69 |
| 420.95 | 1.48 | 1.48 |
| 364.88 | 1.55 | 1.55 |
| 374.92 | 3.11 | 3.11 |
| 346.87 | 2.50 | 2.50 |
| 360.89 | 2.72 | 2.72 |