Basic Information
ID: ALA4312969
Type: ADME
Description: Substrate activity at mEH in human liver microsomes assessed as diol release at 10 uM measured after 60 mins in presence of CYP inhibitor ketoconazole by UPLC-Q-TOF/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4312969
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.54 | 3.95 | 3.95 |
| 476.53 | 2.87 | 2.87 |
| 474.56 | 3.56 | 3.56 |
| 233.31 | 2.06 | 2.06 |
| 462.51 | 2.62 | 2.62 |
| 498.49 | 3.07 | 3.07 |
| 384.48 | 1.83 | 1.83 |
| 482.49 | 3.41 | 3.41 |
| 412.53 | 2.61 | 2.61 |
| 450.47 | 2.61 | 2.61 |
| 398.51 | 2.22 | 2.22 |