Assay Report Card

Basic Information

ID: ALA4313167

Type: Functional

Description: Potentiation of cyclophosphamide-induced cytotoxicity against human XPF-knockout HCT116 cells assessed as reduction in colony formation at 2 uM incubated for 4 hrs prior to 50 uM cyclophosphamide addition for 24 hrs followed by compound washout and subsequent compound redosing and measured after 8 days by crystal violet staining-based assay

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
520.085.185.18