Basic Information
ID: ALA4313179
Type: Binding
Description: Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after 35 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: COS-7
Target: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1(ALA5925)
Document: ALA4311954
Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after 35 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4313179
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 687.86 | 5.03 | 5.03 |
| 789.90 | 8.48 | 8.48 |
| 781.97 | 8.82 | 8.82 |
| 866.14 | 10.79 | 10.79 |
| 889.91 | 10.24 | 10.24 |
| 813.97 | 8.22 | 8.22 |