Basic Information
ID: ALA4313180
Type: Binding
Description: Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production at 100 uM using pNP-TMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after 35 mins relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: COS-7
Target: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1(ALA5925)
Document: ALA4311954
Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production at 100 uM using pNP-TMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after 35 mins relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4313180
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 856.02 | 9.30 | 9.30 |
| 659.81 | 4.35 | 4.35 |
| 657.83 | 6.12 | 6.12 |
| 766.02 | 8.75 | 8.75 |