Basic Information
ID: ALA4313181
Type: Binding
Description: Inhibition of human NPP3 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after 35 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: COS-7
Target: Ectonucleotide pyrophosphatase/phosphodiesterase family member 3(ALA5580)
Document: ALA4311954
Inhibition of human NPP3 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after 35 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4313181
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 789.90 | 8.48 | 8.48 |
| 866.14 | 10.79 | 10.79 |
| 659.81 | 4.35 | 4.35 |
| 889.91 | 10.24 | 10.24 |
| 657.83 | 6.12 | 6.12 |
| 766.02 | 8.75 | 8.75 |
| 813.97 | 8.22 | 8.22 |