Basic Information
ID: ALA4313194
Type: Binding
Description: Inhibition of HIV1 NL4-3 protease I50V/A71V mutant expressed in Escherichia coli TAP-106 cells using EDANS/DABCYL-labelled 10-amino acid containing natural MA/CA cleavage site as substrate preincubated for 1 hr followed by substrate addition and measured for 60 mins by FRET assay
Organism: Human immunodeficiency virus 1
Strain: NL4-3
Activity Charts
Bioactivity
Activity Types for Assay ALA4313194
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.67 | 2.38 | 2.38 |
| 590.74 | 3.24 | 3.24 |
| 592.71 | 1.82 | 1.82 |
| 590.74 | 3.07 | 3.07 |
| 590.74 | 3.24 | 3.24 |
| 592.71 | 1.82 | 1.82 |
| 576.71 | 2.85 | 2.85 |
| 576.71 | 2.85 | 2.85 |
| 606.74 | 2.21 | 2.21 |
| 620.77 | 2.60 | 2.60 |
| 576.71 | 2.68 | 2.68 |
| 606.74 | 2.21 | 2.21 |
| 620.77 | 2.60 | 2.60 |
| 604.77 | 3.63 | 3.63 |
| 604.77 | 3.63 | 3.63 |