Assay Report Card

Basic Information

ID: ALA4313628

Type: ADME

Description: Drug metabolism in Sprague-Dawley rat liver microsomes assessed as CYP450-mediated N-(2-aminoethyl)-2-(aminomethyl)-2-[(3,5-dibromo-4-hydroxy-phenyl)methyl]-3-(3,5-dibromophenyl)propanamide formation incubated up to 3 hrs in presence of NADPH regenerating system by RP-HPLC-MS analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
627.014.544.54