Assay Report Card

Basic Information

ID: ALA4313630

Type: ADME

Description: Drug metabolism in Sprague-Dawley rat liver microsomes assessed as CYP450-mediated 4-[2-(aminomethyl)-3-(3,5-dibromophenyl)-2-(4,5-dihydrooxazol-3-ium-2-yl)propyl]-2,6-dibromo-phenol formation incubated up to 3 hrs in presence of NADPH regenerating system by RP-HPLC-MS analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
627.014.544.54