Basic Information
ID: ALA4313632
Type: ADME
Description: Drug metabolism in Sprague-Dawley rat liver microsomes assessed as CYP450-mediated 4-[2-(aminomethyl)-3-[3,5-bis(trifluoromethyl)phenyl]-2-(4,5-dihydrooxazol-3-ium-2-yl)propyl]-2,6-bis(trifluoromethyl)phenol formation incubated up to 3 hrs in presence of NADPH regenerating system by RP-HPLC-MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4313632
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 583.42 | 5.57 | 5.57 |